Entrepreneurship is a process that plays a critical role in the continued growth and national development plays. Its importance to the point that economists, entrepreneurs are the engine of economic growth and development. Promote women's entrepreneurial activities, effective stimulus to growth and economic development and improve the quality of their life is. The aim of this study was to identify factors affecting the development of entrepreneurship in small businesses (SME) Rural Women Islamabad city was using the techniques of content analysis. This form of qualitative research is done with the participation of 48 entrepreneurship Rural Women Islamabad city. Information is collected through interviews with women entrepreneurs, and Content analysis was used to analyze the data. The content analysis showed that, personal factors, environmental factors, Socio-cultural factors, motivational factors, Education and extension, Policy factors and management factors, the general factors that are influencing the entrepreneurship in small businesses (SME) Rural. Therefore, with regard to the results of the analysis has been done to increase slightly the number of entrepreneurs in rural, Quality improvement category entrepreneurship in rural small businesses (SME) and the culture of entrepreneurship And self-employed in rural communities, especially among rural women whose arms are capable of rural activities, Policy to encourage and support small businesses (SME) Rural women are recommended by the government. Therefore Regarding the variables of each of these components and strengthen them can Motivate women in rural areas and development of the business in the village.