Dust storms known as 120-day winds in Sistan have caused the largest dust center in Nimroz city and the villagers with many problems in the field of economic, social, environmental, health and livelihoods have encountered. Therefore, the goal of this study is to investigate the economic effects of dust on the livelihood of villagers in Nimroz. The statistical population of the study was 895 households that based on krejcie and Morgan table, the number of statistical samples of 318 people was selected by cluster sampling and then using structural equation SMART PLS software and the data is analyzed. The results of the questionnaire data showed that economic analysis by a factor of 0/5 is most effective on rural livelihoods. Statements of this variable include the effect of dust on production costs in the agricultural sector with a coefficient of 0.79 has the greatest impact on the economic sector, followed by a decrease in rural incomes by a coefficient of 0.87, a decrease in land prices by a coefficient of 0/ 78, the amount of crop and garden production with a coefficient of 0.77 and finally agricultural investment with a coefficient of 0.55. Considering the greatest impact of dust on production costs in the agricultural sector, it is suggested that the government should put natural and unnatural preventive measures on the agenda to reduce dust, and also provide financial and non-financial support to farmers to help reduce the production costs of this sector.